The dose of Demerol Injection should be proportionately reduced usually by 25 to 50 percent when administered concomitantly with phenothiazines and many other tranquilizers since they potentiate the action of Demerol Injection. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding. The treatment takes about an hour, and you can usually go home about an hour later. If you are taking this once daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Adults: The usual dosage is 50 mg to 150 mg intramuscularly or subcutaneously every 3 or 4 hours as needed for pain. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely.
Meperidine is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. What should I avoid while taking tolterodine Detrol LA? All of these results will help the doctor figure out how best to treat you.
The safety and effectiveness of meperidine in pediatric patients has not been established. Literature reports indicate that meperidine has a slower elimination rate in neonates and young infants compared to older children and adults. Neonates and young infants may also be more susceptible to the effects, especially the respiratory depressant effects. If meperidine use is contemplated in neonates or young infants, any potential benefits of the drug need to be weighed against the relative risk of the patient. QTdrugs List, AZCERT, Inc. Advise both patients and caregivers about the risks of respiratory depression and sedation when Demerol Injection is used with benzodiazepines or other CNS depressants including alcohol and illicit drugs. Advise patients not to drive or operate heavy machinery until the effects of concomitant use of the benzodiazepine or other CNS depressant have been determined.
The use of Demerol Injection in patients with acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment is contraindicated. Oro Valley, AZ 85755. November 17, 2015. This means you have any two types of the condition. Many women have both stress and urge incontinence. Symptoms may include difficulty breathing; difficulty urinating; dilated pupils; dry mouth; excitation; fast heartbeat; hallucinations; seizures. Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.
Demerol Injection may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of Demerol Injection and know how they will react to the medication. To relieve dry mouth, suck sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. Warn patients of the symptoms of serotonin syndrome and to seek medical attention right away if symptoms develop. Inform your doctor if your condition persists or worsens. Tell your doctor if your condition persists or worsens. Detrol LA extended-release capsules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Demerol Injection may reduce respiratory drive, and the resultant CO 2 retention can further increase intracranial pressure. Monitor such patients for signs of sedation and respiratory depression, particularly when initiating therapy with Demerol Injection. Because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. The concomitant use of acyclovir may increase the plasma concentrations of meperidine and its metabolite, normeperidine. In an individual physically dependent on opioids, administration of the recommended usual dosage of the antagonist will precipitate an acute withdrawal syndrome. The severity of the withdrawal symptoms experienced will depend on the degree of physical dependence and the dose of the antagonist administered. If a decision is made to treat serious respiratory depression in the physically dependent patient, administration of the antagonist should be begun with care and by titration with smaller than usual doses of the antagonist. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. How should I take tolterodine Detrol LA? Studies to determine the effect of meperidine on fertility have not been conducted. For certain products of this drug, an empty tablet shell may appear in your stool. This is harmless. What other drugs will affect tolterodine Detrol?
Pfizer also has programs that provide eligible patients with insurance, support assistance, and medicines at a savings. Contact Pfizer RxPathways for details 844-989-7284. You need to get the condition treated. If your bladder can't empty, that can lead to infections and other problems. Store Detrol LA extended-release capsules at room temperature, between 68 and 77 degrees F 20 and 25 degrees C. Brief storage at temperatures between 59 and 86 degrees F 15 and 30 degrees C is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Detrol LA extended-release capsules out of the reach of children and away from pets. Individually titrate Demerol Injection to a dose that provides adequate analgesia and minimizes adverse reactions. Meperidine produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. glucotrol
Tell your doctor if your condition does not improve or if it worsens. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product. If your symptoms do not improve or if they become worse, check with your doctor. Take this medication by mouth with or without food as directed by your doctor, usually once a day. Swallow the medication whole with a full glass of liquid. Do not crush or chew the medication. Doing so can destroy the long action of the drug and may increase side effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval. How does your doctor know if you really do have a kidney stone? If concomitant use of acyclovir and Demerol Injection is necessary, monitor patients for respiratory depression and sedation at frequent intervals. Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of Demerol Injection in patients with impaired consciousness or coma. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for a long time may have problems. Lifestyle changes and treatments can help with symptoms. slimex otc canada shoppers drug mart slimex
If you are in really bad pain, you probably want to see a doctor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Discontinue Demerol Injection if serotonin syndrome is suspected. The onset of symptoms generally occurs within several hours to a few days of concomitant use, but may occur later than that. Discontinue Demerol Injection if serotonin syndrome is suspected. Abuse and addiction are separate and distinct from physical dependence and tolerance. Health care providers should be aware that addiction may not be accompanied by concurrent tolerance and symptoms of physical dependence in all addicts. In addition, abuse of opioids can occur in the absence of true addiction. Marked mydriasis rather than miosis may be seen due to hypoxia in overdose situations. Swallow this medication with the help of liquids. not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or tells you to do so. Swallow the whole or split tablet without crushing or chewing. Candesartan belongs to a class of drugs called angiotensin receptor blockers ARBs. It works by relaxing vessels so can flow more easily. What are the possible side effects of tolterodine Detrol? Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. Meperidine may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression. Formal reproductive and developmental toxicology studies for meperidine have not been completed. Do not share this medication with others. These are the most common ones. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling. What should I discuss with my healthcare provider before taking tolterodine Detrol?
Then, if needed, she will order tests to get pictures of your kidneys and urinary tract. First, she will get a medical history and examine you. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Demerol Injection is achieved. Similarly, discontinuation of a CYP3A4 inducer, such as rifampin, carbamazepine, and phenytoin, in DEMEROL-Injection treated patients may increase meperidine plasma concentrations and prolong opioid adverse reactions. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. If concomitant use is necessary, consider increasing the Demerol Injection dosage until stable drug effects are achieved. Monitor for signs of opioid withdrawal. If a CYP3A4 or CYP2B6 inducer is discontinued, consider Demerol Injection dosage reduction and monitor for signs of respiratory depression. The opioid antagonists, naloxone or nalmefene, are specific antidotes to respiratory depression resulting from opioid overdose. For clinically significant respiratory or circulatory depression secondary to meperidine overdose, administer an opioid antagonist. Opioid antagonists should not be administered in the absence of clinically significant respiratory or circulatory depression secondary to meperidine overdose. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. tosaf.info adapalene
It decreases your 's response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. Serotonin syndrome: Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation see above drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. This medication is not recommended for use in children younger than 1 year due to increased risk of side effects. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Consult your pharmacist for further advice. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Blunt cannulas should not be recapped, purposely bent or broken by hand. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. Meperidine produces peripheral vasodilation which may result in orthostatic hypotension or syncope. Tolterodine may also be used for purposes not listed in this medication guide. Gastrointestinal. Dry mouth, constipation, biliary tract spasm. costco price for dexamethasone otc
Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. Opioids are sought by drug abusers and people with addiction disorders and are subject to criminal diversion. Consider these risks when prescribing or dispensing Demerol Injection. Strategies to reduce these risks include prescribing the drug in the smallest appropriate quantity. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Moderate. These medicines may cause some risk when taken together. Meperidine causes a reduction in motility associated with an increase in smooth muscle tone in the antrum of the stomach duodenum. Digestion of food in the small intestine is delayed and propulsive contractions are decreased. Propulsive peristaltic waves in the colon are decreased, while tone may be increased to the point of spasm, resulting in constipation. Other opioid-induced effects may include a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase. Cordarone, Pacerone dofetilide Tikosyn disopyramide Norpace procainamide Procan, Pronestyl quinidine Quin-G or sotalol Betapace. Allergic. Pruritus, urticaria, other skin rashes, wheal and flare over the vein with intravenous injection. Meperidine is metabolized through biotransformation. In vitro data show meperidine is metabolized to normeperidine in liver mainly by CYP3A4 and CYP2B6. Overdose symptoms may include dry mouth, blurred vision, and fast heartbeat. Carpuject are packaged in a Slim-Pak tamper detection package. Note that a needle is not included. Although may be used to prevent problems or treat people who have problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking candesartan. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine. Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. Demerol Injection is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including Demerol Injection, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions. However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression. Catheter. Some people use a catheter to make sure their bladder is emptied. It's a thin plastic tube that you insert in your urethra. A doctor or nurse can teach you how to insert it for yourself. This list is not complete and there are many other drugs that can interact with tolterodine. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. Other. Pain at injection site; local tissue irritation and induration following subcutaneous injection, particularly when repeated; antidiuretic effect.
Cut back on sodium and salty foods: Lots of sodium can raise calcium levels in your urine. And that can cause stones to form. This may interfere with certain laboratory tests such as possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Check the Rx Outreach website for the exact price and most current medication list. The following adverse reactions associated with the use of meperidine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. In case of overdose, priorities are the reestablishment of a patent and protected airway and institution of assisted or controlled ventilation, if needed. Employ other supportive measures including oxygen and vasopressors in the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require advanced life-support techniques. diphenhydramine generika online bestellen
If any of these effects persists or worsens, tell your doctor or promptly. Long-term studies in animals to evaluate the carcinogenic potential of meperidine have not been conducted. It repositions the urethra to help reduce leakage. If you do not take the same dose each day or if you take this medication every other day, ask your doctor or what you should do if you miss a dose. If the level of pain increases after dosage stabilization, attempt to identify the source of increased pain before increasing the Demerol Injection dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between management of pain and opioid-related adverse reactions. In severe overdose, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. Blurred vision; constipation; dizziness; drowsiness; dry eyes; dry mouth; headache; indigestion; stomach pain. Concomitant use of Demerol Injection with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could decrease meperidine plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to meperidine. Ask your health care provider any questions you may have about how to use Detrol LA extended-release capsules. Take Detrol LA extended-release capsules by mouth with or without food. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Do 3 or 4 sets daily. HCl, and it has the following chemical structure. This program provides uninsured patients with savings on their prescriptions at the pharmacy. discount gemfibrozil online
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While serious, life-threatening, or fatal respiratory depression can occur at any time during the use of Demerol Injection, the risk is greatest during the initiation of therapy or following a dosage increase. Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy with and following dosage increases of Demerol Injection. Medications, electrical stimulation, or surgery. Doctors sometimes prescribe medicines that block the of an overactive bladder. Electrical stimulation of the bladder nerves helps in some cases. Surgery is reserved for severe cases. It aims to increase the amount of urine your bladder can store. phenazopyridine
To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage. Demerol Injection should not be used for treatment of chronic pain.
Demerol Injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Report prolonged or to your doctor. Demerol Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia. While many dieters swear by high-, eating large amounts of can also cause a stone to form. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation.
Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Do not stop taking this medication without consulting your doctor. The half-life of meperidine is 2 to 5 hours, and the half-life of normeperidine is 15 to 30 hours. Take this by with or without food as directed by your doctor, usually once or twice daily.